AIUPred - Prediction of Intrinsically Unstructured Proteins

Intrinsically disordered proteins (IDPs) have no single well-defined tertiary structure under native conditions. AIUPred is a web interface that allows to identify disordered protein regions. AIUPred is also capable of identifying protein regions that do or do not adopt a stable structure depending on protein binding (ANCHOR2) or based on the change in redox state of their environment. AIUPred supersedes the previous IUPred and ANCHOR servers.

The AIUPred web server can be accessed for free.


Context dependent disorder
Additional options
Primary citation
AIUPred: combining energy estimation with deep learning for the enhanced prediction of protein disorder
Gábor Erdős, Zsuzsanna Dosztányi
Nucleic Acids Research 2024; gkae385